Studien

• Pancreatogastrostomy versus pancreatojejunostomy for RECOnstruction after partial PANCreatoduodenectomy (RECOPANC): study protocol of a randomized controlled trial UTN U1111-1117-9588

  Wellner UF, Brett S, Bruckner T, Limprecht R, Rossion I, Seiler C, Sick O, Wegener I, Hopt UT, Keck T

  Trials. 2012 Apr 27;13(1):45

• A comparison of intervention and conservative treatment for angulated fractures of the distal forearm in children (AFIC): study protocol for a randomized controlled trial

  Adrian M, Wachtlin D, Kronfeld K, Sommerfeldt D, Wessel LM

  Trials. 2015 Sep 30;16:437

• A historically controlled, single-arm, multi-centre, prospective trial to evaluate the safety and efficacy of MonoMax suture material for abdominal wall closure after primary midline laparotomy. ISSAAC-Trial [NCT005725079]

  Fischer L, Baumann P, Hüsing J, Seidlmayer C, Albertsmeier M, Franck A, Luntz S, Seiler CM, Knaebel HP

  BMC Surg 2008; 8:21

• Adenocarcinomas of the Esophagogastric Junction Are More Likely to Respond to Preoperative Chemotherapy than Distal Gastric Cancer

  Reim D, Gertler R, Novotny A, Becker K, Büschenfelde CM, Ebert M, Dobritz M, Langer R, Hoefler H, Friess H, Schumacher C

  Ann Surg Oncol 2011

• BariSurg trial: Sleeve gastrectomy versus Roux-en-Y gastric bypass in obese patients with BMI 35-60 kg/m(2) - a multi-centre randomized patient and observer blind non-inferiority trial

  Fischer L, Wekerle AL, Bruckner T, Wegener I, Diener MK, Frankenberg MV, Gärtner D, Schön MR, Raggi MC, Tanay E, Brydniak R, Runkel N, Attenberger C, Son MS, Türler A, Weiner R, Büchler MW, Müller-Stich BP

  BMC Surg. 2015 Jul 18;15:87

• CERAMENT treatment of fracture defects (CERTiFy): protocol for a prospective, multicenter, randomized study investigating the use of CERAMENT™ BONE VOID FILLER in tibial plateau fractures

  Nusselt T, Hofmann A, Wachtlin D, Gorbulev S, Rommens PM

  Trials 2014 Mar 8;15:75

• ChroPac-Trial: Duodenum-preserving pancreatic head resection versus pancreatoduodenectomy for chronic pancreatitis. Trial protocol of a randomised controlled multicentre trial

  Markus K Diener, Thomas Bruckner, Pietro Contin, Christopher Halloran, Matthias Glanemann, Hans Jurgen Schlitt, Joachim Mossner, Meinhard Kieser, Jens Werner, Markus W Buchler and Christoph M Seiler

  Trials 2010 April 29; 11:47

• Clinical trials in gastric cancer and the future

  Mihaljevic AL, Friess H, Schuhmacher C

  J Surg Oncol. 2012 Apr 18

• CoCStom trial: study protocol for a randomised trial comparing completeness of adjuvant chemotherapy after early versus late diverting stoma closure in low anterior resection for rectal cancer

  Sandra-Petrescu F, Herrle F, Hinke A, Rossion I, Suelberg H, Post S, Hofheinz RD, Kienle P

  BMC Cancer. 2015 Nov 21;15(1):923.

• Comparison of standard fusion with a "topping off" system in lumbar spine surgery: a protocol for a randomized controlled trial

  Siewe J, Otto C, Knoell P, Koriller M, Stein G, Kaulhausen T, Eysel P, Zarghooni K, Franklin J, Sobottke R

  BMC Musculoskelet Disord 2011; 12:239

• Comparison of total parathyroidectomy without autotransplantation and without thymectomy versus total parathyroidectomy with autotransplantation and with thymectomy for secondary hyperparathyroidism: TOPAR PILOT-Trial

  Schlosser K, Veit JA, Witte St, Fernandez E, Victor N, Knaebel H-P, Seiler CM, Rothmund M

  Trials 2007; 8:22

• Continuous intraoperative monitoring of pelvic autonomic nerves during TME to prevent urogenital and anorectal dysfunction in rectal cancer patients (NEUROS): a randomized controlled trial

  Kauff DW, Kronfeld K, Gorbulev S, Wachtlin D, Lang H, Kneist W

  BMC Cancer. 2016 May 21;16:323

• CRASH2 in Germany [ISRCTN 86750102]

  Chung CH, Freiberger A, Kalkum M, Luntz SP, Shakur H, Seiler CM

  Trials 2006; 7:22

• Design and current status of CONTINT: continuous versus interrupted abdominal wall closure after emergency midline laparotomy - a randomized controlled multicenter trial [NCT00544583]

  Rahbari NN, Knebel P, Kieser M, Bruckner T, Bartsch DK, Friess H, Mihaljevic AL, Stern J, Diener MK, Voss S, Rossion I, Buechler MW, Seiler CM

  Trials. 2012 May 30;13(1):72

• Development of a clinical trial to determine whether watchful waiting is an acceptable alternative to surgical repair for patients with oligosymptomatic incisional hernia: study protocol for a randomized controlled trial

  Lauscher JC, Martus P, Stroux A, Neudecker J, Behrens U, Hammerich R, Buhr HJ, Ritz JP

  Trials 2012; 13:14

• Die ABC-Studie. Hintergrund und Studienaufbau

  Zimmermann A, Berger H, Eckstein HH.

  Gefäßchirurgie 2010; 15:5-10

• DISPACT: A randomized controlled trial to compare two different surgical techniques of Distal Pancreatectomy: Study rationale and design (ISRCTN 18452029)

  Diener MK, Knaebel HP, Witte St, Büchler MW, Seiler CM and the DISPACT Trial Group (2007)

  Clinical Trials 2008; 5:534

• Duodenum-preserving pancreatic head resection--a randomized controlled trial comparing the original Beger procedure with the Berne modification (ISRCTN No. 50638764).

  Köninger J, Seiler CM, Sauerland S, Wente MN, Reidel MA, Müller MW, Friess H, Büchler MW.

  Surgery 2008; 143:490-8

• Effectiveness of triclosan-coated PDS Plus versus uncoated PDS II sutures for prevention of surgical site infection after abdominal wall closure: the randomised controlled PROUD trial

  Diener MK, Knebel P, Kieser M, Schüler P, Schiergens TS, Atanassov V, Neudecker J, Stein E, Thielemann H, Kunz R, von Frankenberg M, Schernikau U, Bunse J, Jansen-Winkeln B, Partecke LI, Prechtl G, Pochhammer J, Bouchard R, Hodina R, Beckurts KT, Leißner L, Lemmens HP, Kallinowski F, Thomusch O, Seehofer D, Simon T, Hyhlik-Dürr A, Seiler CM, Hackert T, Reissfelder C, Hennig R, Doerr-Harim C, Klose C, Ulrich A, Büchler MW

  Lancet 2014 Jul 12; 384(9938):142-52

• Efficacy of stapler versus hand-sewn closure after distal pancreatectomy (DISPACT): a randomised, controlled multicentre trial

  Diener MK, Seiler CM, Rossion I, Kleeff J, Glanemann M, Butturini G, Tomazic A, Bruns CJ, Busch OR, Farkas S, Belyaev O, Neoptolemos JP, Halloran C, Keck T, Niedergethmann M, Gellert K, Witzigmann H, Kollmar O, Langer P, Steger U, Neudecker J, Berrevoet F, Ganzera S, Heiss MM, Luntz SP, Bruckner T, Kieser M, Büchler MW.

  Lancet 2011; 337(9776):1514-22

• Frequency of pneumothorax and haemothorax after primary open versus closed implantation strategies for insertion of a totally implantable venous access port in oncological patients: study protocol for a randomised controlled trial

  Hüttner FJ, Bruckner T, Alldinger I, Hennes R, Ulrich A, Büchler MW, Diener MK, Knebel P

  Trials. 2015;16:128

• HAnd Suture Versus STApling for Closure of Loop Ileostomy (HASTA Trial): Results of a Multicenter Randomized Trial (DRKS00000040)

  Löffler T, Rossion I, Bruckner T, Diener MK, Koch M, von Frankenberg M, Pochhammer J, Thomusch O, Kijak T, Simon T, Mihaljevic AL, Krüger M, Stein E, Prechtl G, Hodina R, Michal W, Strunk R, Henkel K, Bunse J, Jaschke G, Politt D, Heistermann HP, Fuer M, Lange C, Stamm A, Vosschulte A, Holzer R, Partecke LI, Burdzik E, Hug HM, Luntz SP, Kieser M, Büchler MW, Weitz J; the HASTA Trial Group

  Ann Surg. 2012 Nov;256(5):828-836

• HAnd-suture versus STApling for Closure of Loop Ileostomy: HASTA-Trial: a study rationale and design for a randomized controlled trial

  Loffler T, Seiler CM, Rossion I, Kijak T, Thombusch O, Hodina R, Kruger M, Simon T, Bruckner T, Kieser M, Buchler MW, Weitz J, Group HT.

  Trials 2011; 12(1):34

• Interrupted or Continuous Slowly Absorbable Sutures For Closure of Primary Elective Midline Abdominal Incisions: A Multicenter Randomized Trial (INSECT: ISRCTN24023541)

  Seiler CM, Bruckner T, Diener MK, Papyan A, Golcher H, Seidlmayer C, Franck A, Kieser M, Büchler MW, Knaebel HP.

  Ann Surg 2009; 249(4):576-82

• Intravenous versus epidural analgesia to reduce the incidence of gastrointestinal complications after elective pancreatoduodenectomy (the PAKMAN trial, DRKS 00007784): study protocol for a randomized controlled trial

  Klotz R, Hofer S, Schellhaaß A, Dörr-Harim C, Tenckhoff S, Bruckner T, Klose C, Diener MK, Weigand MA, Büchler MW, Knebel P

  Trials. 2016 Apr 11;17(1):194

• Multicenter Double-Blinded Randomized Controlled Trial of Standard Abdominal Wound Edge Protection With Surgical Dressings Versus Coverage With a Sterile Circular Polyethylene Drape for Prevention of Surgical Site Infections: A CHIR-Net Trial (BaFO; NCT01

  Mihaljevic AL, Schirren R, Ozer M, Ottl S, Grün S, Michalski CW, Erkan M, Jäger C, Reiser-Erkan C, Kehl V, Schuster T, Roder J, Clauer U, Orlitsch C, Hoffmann TF, Lange R, Harzenetter T, Steiner P, Michalski M, Henkel K, Stadler J, Pistorius GA, Jahn A, Obermaier R, Unger R, Strunk R, Willeke F, Vogelsang H, Halve B, Dietl KH, Hilgenstock H, Meyer A, Krämling HJ, Wagner M, Schoenberg MH, Zeller F, Schmidt J, Friess H, Kleeff J.

  Ann Surg 2014 Nov;260(5):730-9

• Open reduction and internal fixation versus casting for highly comminuted and intra-articular fractures of the distal radius (ORCHID): protocol for a randomized clinical multi-center trial

  Bartl C, Stengel D, Bruckner T, Rossion I, Luntz S, Seiler CM, Gebhard F

  Trials 2011; 12-84

• Operative standardization in randomized controlled surgical trials. Meeting of the INSECT trial

  Knaebel HP, Kirschner MH, Reidel MA, Büchler MW, Seiler CM (2006)

  Chirurg 2006; 77(3):267-72, German

• Pancreatogastrostomy Versus Pancreatojejunostomy for RECOnstruction After PANCreatoduodenectomy (RECOPANC, DRKS 00000767): Perioperative and Long-term Results of a Multicenter Randomized Controlled Trial

  Keck T, Wellner UF, Bahra M, Klein F, Sick O, Niedergethmann M, Wilhelm TJ, Farkas SA, Börner T, Bruns C, Kleespies A, Kleeff J, Mihaljevic AL, Uhl W, Chromik A, Fendrich V, Heeger K, Padberg W, Hecker A, Neumann UP, Junge K, Kalff JC, Glowka TR, Werner J, Knebel P, Piso P, Mayr M, Izbicki J, Vashist Y, Bronsert P, Bruckner T, Limprecht R, Diener MK, Rossion I, Wegener I, Hopt UT

  Ann Surg. 2015 Jul 1

• Perioperative management in distal pancreatectomy: results of a survey in 23 European participating centres of the DISPACT trial and a review of literature

  Bruns H, Rahbari NN, Löffler T, Diener MK, Seiler CM, GlanemannM, Butturini G, Schuhmacher C, Rossion I, Büchler MW, Junghans T, DISPACT Trial Group

  Trials 2009; 10:58

• Prevention of abdominal wound infection (PROUD trial, DRKS00000390): study protocol for a randomized controlled trial

  Heger U, Voss S, Knebel P, Doerr-Harim C, Neudecker J, Schuhmacher C, Faist E, Diener MK, Kieser M, Seiler CM, Buchler MW

  Trials 2011; 12(1):245

• Protocol design and current status of CLIVIT: A randomized controlled multicenter relevance trial comparing clips versus ligatures in thyroid surgery (ISRCTN 96901396)

  Seiler CM, Fröhlich BE, Veit JA, Gazyakan E, Wente MN, Knauer C, Deckert A, Witte S, Victor N, Büchler MW, Knaebel HP and the CLIVIT Study Group (2006)

  Trials 2006; 7(1):27

• Pulmonary wedge resection plus parietal pleurectomy (WRPP) versus parietal pleurectomy (PP) for the treatment of recurrent primary pneumothorax – WOPP-trial: study protocol for a randomized controlled trial

  Neudecker J, Malzahn U, Heuschmann P, Behrens U, Walles T

  Trials. 2015 Nov 30;16:540

• Randomized controlled trial of ultrasonic dissection versus standard surgical technique in open left hemicolectomy or total gastrectomy

  Wilhelm D, Szabo M, Glass F, Schuhmacher C, Friess H, Feussner H

  Br J Surg 2011; 98(2):220-7

• Resection of the primary tumour versus no resection prior to systemic therapy in patients with colon cancer and synchronous unresectable metastases (UICC stage IV): SYNCHRONOUS - A randomised controlled multicentre trial (ISRCTN30964555)

  Rahbari NN, Lordick F, Fink C, Bork U, Stange A, Jager D, Luntz SP, Englert S, Rossion I, Koch M, Buchler MW, Kieser M, Weitz J

  BMC Cancer 2012; 12(1):142

• Resection of the primary tumour versus no resection prior to systemic therapy in patients with colon cancer and synchronous unresectable metastases (UICC stage IV): SYNCHRONOUS--a randomised controlled multicentre trial (ISRCTN30964555)

  Rahbari NN, Lordick F, Fink C, Bork U, Stange A, Jäger D, Luntz SP, Englert S, Rossion I, Koch M, Büchler MW, Kieser M, Weitz J; SYNCHRONOUS trial group

  BMC Cancer 2012; 12:142

• Short-term Results of a Randomized Controlled Trial Comparing Primary Suture With Primary Glued Mesh Augmentation to Prevent Incisional Hernia

  Timmermans L1, Eker HH, Steyerberg EW, Jairam A, de Jong D, Pierik EG, Lases SS, van der Ham AC, Dawson I, Charbon J, Schuhmacher C, Izbicki JR, Neuhaus P, Knebel P, Fortelny R, Kleinrensink GJ, Jeekel J, Lange JF

  Ann Surg 2014 Jun 30

• Standard abdominal wound edge protection with surgical dressings vs coverage with a sterile circular polyethylene drape for prevention of surgical site infections (BaFO): study protocol for a randomized controlled trial

  Mihaljevic AL, Michalski CW, Erkan M, Reiser-Erkan C, Jäger C, Schuster T, Schuhmacher C, Kleeff J, Friess H

  Trials. 2012 May 15;13:57

• The treatment of displaced intra-articular distal radius fractures in elderly patients

  Bartl C, Stengel D, Bruckner T, Gebhard F; ORCHID Study Group

  Dtsch Arztebl Int 2014; 111(46): 779-87

• Total Parathyroidectomy With Routine Thymectomy and Autotransplantation Versus Total Parathyroidectomy Alone for Secondary Hyperparathyroidism - Results of a Nonconfirmatory Multicenter Prospective Randomized Controlled Pilot Trial

  Schlosser K, Bartsch DK, Diener MK, Seiler CM, Bruckner T, Nies C, Meyer M, Neudecker J, Goretzki PE, Glockzin G, Konopke R, Rothmund M

  Ann Surg 2016 [ahead of print]

• Vakuum-assistierte Wundbehandlung bei diabetischen Fußwunden - eine randomisierte kontrollierte Studie innerhalb der integrierten Versorgung

  Sauerland S, Seidel D, Walgenbach M, Affüpper- Fink M, Neugebauer EAM.

  Z Allg Med 2009; Sonderausgabe:82

• Vakuum-assistierte Wundbehandlung bei diabetischen Fußwunden - eine randomisierte kontrollierte Studie innerhalb der integrierten Versorgung

  Seidel D, Walgenbach M, Sauerland S, Neugebauer EAM.

  Vasa 2009; 38:68

• Vascular clips versus ligatures in thyroid surgery-results of a multicenter randomized controlled trial (CLIVIT Trial)

  Diener MK, Seiler CM, von Frankenberg M, Rendel K, Schüle S, Maschuw K, Riedl S, Rückert JC, Eckmann C, Scharlau U, Ulrich A, Bruckner T, Knaebel HP, Rothmund M, Büchler MW; for the CLIVIT Study Group

  Langenbecks Arch Surg. 2012 Oct;397(7):1117-1126